CleaveLand4 has been developed and released. This is a full re-build of the CleaveLand software. It now features single command analysis (no more separate scripts!), and also has the ability to perform all phases of analysis. This includes aligning degradome data to the reference, generating a list of potential target sites, and the analysis itself. T-plot generation is also integrated in the single command. Identification of potential target sites is much more sensitive, owing to the use of the new 'GSTAr.pl' aligner (Generic Small RNA-Transcriptome Aligner). This method uses RNAplex to find potential target sites based on RNA-RNA thermodyamics. As such, it is slower than sequence-based alignments, but much better at finding a comprehensive list of all p
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-- THIS WEBSITE HAS BEEN REPLACED ... please go to http://sites.psu.edu/axtell for the current Axtell Lab Website! --AuthorMichael Axtell, lab PI Archives
July 2015
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